Bleeding disorders are a group of disorders that share the inability to form a proper blood clot. Symptoms include extended bleeding after injury, surgery, trauma, or menstruation. Sometimes the bleeding is spontaneous, without a known or identifiable cause. Improper clotting can be caused by defects in blood components such as platelets and/or clotting proteins, also called clotting factors. The body produces 13 clotting factors. If any of them are defective or deficient, blood clotting is affected; a mild, moderate or severe bleeding disorder can result. (National Hemophilia Foundation)
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Sickle cell disease is a group of inherited red blood cell disorders that affects hemoglobin, the protein that carries oxygen through the body. Normally, red blood cells are disc-shaped and flexible to move easily through the blood vessels. For the person with sickle cell disease, the red blood cells are crescent or “sickle” shaped. These cells do not bend and move easily and can block blood flow to the rest of the body.
The blocked blood flow through the body can lead to serious problems, including stroke, eye problems, infections and episodes of pain, called pain crises. (NIH)
